ABSTRACT
Objective: To evaluate the use of the non-invasive ventilation in the treatment of children with acute respiratory failure. Methods: A systematic review of literature was conducted in MEDLINE, LILACS, EMBASE and Cochrane Library databases and references of articles. Blood oxygenation, ventilation and survival were the outcomes evaluated. Results: Until May 2010, 120 publications related to non-invasive ventilation were found. Only 19 of them were clinical trials focused on the use of non-invasive ventilation in children. There are already prospective clinical trials and cohort studies to support a quality of evidence level II concerning the use of non-invasive ventilation in children. Conclusions: There is moderate evidence to support the non-invasive ventilation use in children, with a B-II grade of recommendation.
Objetivo: Avaliar o papel da ventilação não invasiva no tratamento de crianças com insuficiência respiratória aguda. Métodos: Revisão sistemática da literatura sobre ventilação não invasiva nas bases MEDLINE, LILACS, EMBASE e Cochrane, além de referências de artigos. Os desfechos avaliados foram resposta sobre a oxigenação e ventilação sanguínea, e a sobrevida dos pacientes. Resultados: Foram encontrados 120 estudos sobre ventilação não invasiva até Maio de 2010. Destes, apenas 19 eram sobre ventilação não invasiva em crianças. Já há ensaios clínicos prospectivos e de coorte, levando a uma qualidade de evidência nível II sobre o uso de ventilação não invasiva em crianças. Conclusão: Já há evidência científica para recomendar o uso da ventilação não invasiva, com um grau de recomendação B-II.
Subject(s)
Humans , Male , Female , Child , Hypercapnia , Hypoxia , Pulmonary Ventilation , Respiratory InsufficiencyABSTRACT
OBJECTIVE: To assess the role of noninvasive ventilation in the treatment of children with acute respiratory failure. METHODS: A systematic review of literature on noninvasive ventilation in MEDLINE, LILACS, EMBASE, and Cochrane databases, besides references in articles. The outcomes evaluated were responses in blood oxygenation and ventilation, and patient survival. RESULTS: A total of 120 studies on noninvasive ventilation were found as of May, 2010. Of these, only 19 were about noninvasive ventilation in children. On the other hand, there are prospective and cohort clinical trials leading to a level II quality of evidence concerning the use of noninvasive ventilation in children. CONCLUSION: There is scientific evidence for proposing the use of noninvasive ventilation, with a B-II degree of recommendation.
